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After using Mirapex for approximately a year, it slowly became less effective. Although I had been without any symptoms of RLS, I now began to experience increasing episodes of RLS. With the help of my doctor, I have used different combinations of medicines (including Mirapex) until we found the right one. It seems prolonged use of some medicines can make them less effective. Sometimes changing the regimen with professional help can keep RLS at bay.

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So far I would say that this is a good medicine for RLS and I haven't had any side effects.

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Hallucinations, pathologic gambling and other compulsive behaviors, and orthostatic hypotension are uncommon in patients taking higher doses of pramipexole for Parkinson's disease and are seen even less in patients taking lower doses for RLS.

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However, in many cases, a low dose of Pramipexole can offset any such issue.

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While we adjusted the risk estimates for several major confounders, there may have been some residual confounding from unmeasured covariates such as disease severity, as we did not have information on the severity of motor and non-motor symptoms of the disease or of the presence of motor complications of medications, for example.

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CONCLUSIONS: Pramipexole was a safe and effective antidepressant among patients with bipolar depression.

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Here is a collection of user reviews for the medication Mirapex ER sorted by most helpful.

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For hospitals and health system leaders, boards and medical staff, this study deserves discussion.

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The fact is that these medicines may be fake, substandard, and potentially dangerous.

Pramipexole is an effective agent against subjective tinnitus associated with presbycusis at a dose schedule used for the treatment of Parkinson's disease.

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However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

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We asked a very basic question: How does ones sleep duration relate to being diagnosed with clinical dementia in the future.

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Despite media hype to the contrary, it is extremely unusual for a child to be accurately diagnosed with autism and then recover perfect normalcy.

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Follow your doctor's instructions about tapering your dose.

Today, I noticed that he had some twitching under his right eye and wondered if this might be some early signs of Tardive Dyskinesia related to Namenda?

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In a July 2005 Mayo Clinic researchers reported in the Archives of Neurology more documented behavior that supported earlier observations linking dopamine agonist drugs with gambling addiction and compulsive behaviors.

In the clinical development program for immediate-release pramipexole tablets, a single case of rhabdomyolysis occurred in a 49-year-old male with advanced Parkinson's disease.

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To control for potential confounding, we identified several factors in addition to the matching factors that include the drug indication, age, sex, new user status and year of cohort entry.

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However, the treatment with 100 microM pramipexole did not protect SH-SY5Y cells against lactacystin-induced cell toxicity and proteasome dysfunction.

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